Publications by authors named "A E Andreazzi"
Article Synopsis
- Early menarche (before age 12) is linked to a higher risk of hypertension in premenopausal women, with a 58% increased likelihood of developing it, even when accounting for age, obesity, and smoking.
- The study analyzed data from 1406 women aged 18-100, comparing factors like age at menarche, menopausal status, and hypertension indicators.
- In postmenopausal women, early menarche did not independently predict hypertension, as age and other health issues became more significant factors.
Antiobesity, hepatoprotective and anti-hyperglycemic effects of a pharmaceutical formulation containing Cecropia pachystachya Trécul in mice fed with a hypercaloric diet.
J Ethnopharmacol
November 2021
Ethnopharmacological Relevance: The leaves of Cecropia pachystachya Trécul (Urticaceae), known as embaúba, are used as hypoglycemic and for weight reduction in Brazilian traditional medicine.
Aim Of The Study: This study investigated the effects of a pharmaceutical formulation (ECP20) containing C. pachystachya extract on some metabolic alterations caused by a hypercaloric diet in mice.
Maternal soy protein isolate diet during lactation programs deleterious effects on hepatic lipid metabolism, atherogenic indices, and function of adrenal in adult rat offspring.
J Dev Orig Health Dis
April 2022
Article Synopsis
- Soy consumption offers various health benefits, but its phytoestrogen content raises concerns during lactation and pregnancy, prompting a study on its cardiovascular effects on lactating rats and their offspring.
- Lactating rats were divided into groups based on diet (soy protein isolate, soybean, casein), revealing that both soy protein and soybean reduced atherogenic indices (cholesterol ratios) in offspring compared to the control group.
- While the soybean group's offspring showed lower oxidative stress, the soy protein isolate group had negative long-term effects, like increased liver cholesterol and worsened atherogenic indices in adulthood, suggesting caution in soy protein consumption during lactation.
Studies indicate that rapid weight gain at critical development stages, such as the lactation period, is associated with the development of obesity, cardiovascular diseases, and diabetes in the long term. In addition to metabolic changes during adulthood, overweight/obesity may influence reproductive function. Human and animal studies suggest that lifestyle changes through exercise and/or controlled diet result in improved semen quality in obese individuals.
View Article and Find Full Text PDFIncreased fat and carbohydrate intakes based on the Western diet are important lifestyle modifications that lead to hypercaloric inputs, obesity, and male fertility negative effects. Epigenetic transmission may also predispose descended generations to chronic diseases, such as obesity, type 2 diabetes, behavioral, and reproductive disorders. The present study sought to evaluate the influence of a high-fat-high-sugar (HFHS) diet supplied to Wistar rats from 25 to 90 days of life on reproductive and metabolic parameters in male generations F0, F1, and F2.
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