Publications by authors named "A Duggal"
Background: Pulse pressure variation (PPV) is limited in low tidal volume mechanical ventilation. We conducted this systematic review and meta-analysis to evaluate whether passive leg raising (PLR)-induced changes in PPV can reliably predict preload/fluid responsiveness in mechanically ventilated patients with low tidal volume in the intensive care unit.
Methods: PubMed, Embase, and Cochrane databases were screened for diagnostic research relevant to the predictability of PPV change after PLR in low-tidal volume mechanically ventilated patients.
Right ventricular injury (RVI) in respiratory failure receiving veno-venous extracorporeal membrane oxygenation (VV ECMO) is associated with significant mortality. A scoping review is necessary to map the current literature and guide future research regarding the definition and management of RVI in patients receiving VV ECMO. We searched for relevant publications on RVI in patients receiving VV ECMO in Medline, EMBASE, and Web of Science.
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- The study investigates the effectiveness of two weight-based dosing strategies for atracurium in obese patients with acute respiratory distress syndrome (ARDS) during the COVID pandemic, focusing on oxygenation changes after treatment.
- It compares the outcomes of patients receiving atracurium based on actual body weight (ABW) versus ideal body weight (IBW), finding no significant difference in oxygenation improvement after 48 hours despite different dosing amounts.
- The results indicated higher atracurium doses in the ABW group, but no differences in mortality rates or days free from ICU or ventilator support, suggesting both dosing methods may be equally viable for this patient population.
Importance: Receipt of fluid and vasopressors, common treatments in septic shock, may affect cardiac function.
Objectives: We sought to determine whether a liberal or restrictive fluid resuscitation strategy was associated with changes in cardiac function.
Design: We prospectively studied a subset of patients enrolled in the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) trial, performing echocardiography at baseline and at 24 hours after randomization.
Examining the cumulative evidence from randomized controlled trials (RCTs), evaluating the use of pharmacological agents for the treatment of COVID-19 infections in patients with critical illness. Databases Medline, Embase, Web of Science, Scopus, CINAHL, and Cochrane. Study Selection: Inclusion criteria were RCTs that enrolled patients with confirmed or suspected COVID-19 infection who are critically ill.
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