Publications by authors named "A Ducharme"

Background: Heart donation (HD) by those with death determination by circulatory criteria (DDCC) has been proposed as a method to increase the heart donor pool in response to the growing need for heart transplantation (HT). However, the potential level of HD after DDCC in the province of Québec has not yet been reported. This study aims to assess the suitability for HD among donors with DDCC, and to estimate its impact on HT activity.

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The "International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates-2024" updates and replaces the "Listing Criteria for Heart Transplantation: International Society for Heart and Lung Transplantation Guidelines for the Care of Cardiac Transplant Candidates-2006" and the "2016 International Society for Heart Lung Transplantation Listing Criteria for Heart Transplantation: A 10-year Update." The document aims to provide tools to help integrate the numerous variables involved in evaluating patients for transplantation, emphasizing updating the collaborative treatment while waiting for a transplant. There have been significant practice-changing developments in the care of heart transplant recipients since the publication of the International Society for Heart and Lung Transplantation (ISHLT) guidelines in 2006 and the 10-year update in 2016.

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Article Synopsis
  • Elevated levels of interleukin-6 (IL-6) are linked to worse health outcomes, including higher mortality rates and heart failure, in patients regardless of existing cardiovascular disease (CVD).
  • This study analyzed data from the Multi-Ethnic Study of Atherosclerosis (MESA) to explore the relationship between IL-6 levels and various health outcomes across different racial and ethnic groups, finding that those in the highest IL-6 category faced significantly greater risks.
  • The findings indicate that high IL-6 levels are consistently associated with increased all-cause and cardiovascular mortality, as well as heart failure, impacting individuals across diverse racial and ethnic backgrounds.
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