Cost-utility analysis of clinic-based deroofing versus local excision for hidradenitis suppurativa.

Background: Deroofing and local excision are common clinic-based surgical options for hidradenitis suppurativa. Evidence suggests deroofing may have lower rates of adverse events (AEs), defined as disease recurrence or postsurgical complications.

Objective: This cost-utility analysis evaluates the economic and health-related impacts of clinic-based deroofing vs excision for hidradenitis suppurativa, comparing direct medical costs and quality-adjusted life-years (QALYs).

Risk factors and temporal associations of progression of the atopic march in children with early-onset atopic dermatitis.

Background: Risk factors and the temporal relationship between atopic dermatitis (AD) and atopic march remain understudied.

Objective: Determine risk factors for atopic march in early-onset AD patients and the temporality between AD and atopic march.

Methods: We used the MarketScan Research Database for our retrospective cohort analysis from 2010 to 2018, comparing infants diagnosed with AD before age 1 with controls without early-onset AD.

Attaining conservation goals for quinoa: Implications for public policy in Peru and beyond.

Worldwide many crop varieties are considered seriously threatened while management strategies are still lacking. Goals and indicators relevant to the conservation of agrobiodiversity also remain to be developed. Here we present the results of three expert workshops in Peru designed to prioritise for conservation crops with high infra-specific diversity, along with the establishment of in-situ on-farm conservation goals and indicators.