Value of MRI in the diagnosis and staging of testicular tumors.

Ultrasound is currently the primary imaging modality for the assessment of scrotal disease. In acute pathology, colour Doppler adds further confirmation about blood flow to the testicles and surrounding structures. MR is emerging as a powerful tool to image the scrotum.

Curative irradiation of the entire orbit in rhabdomyosarcoma: a case report.

Rhabdomyosarcoma (RMS) is a relatively frequent tumor in children. Judicious combinations have markedly improved treatment results in recent years. Orbital localizations are treated with chemotherapy and radiotherapy.

Isochromosome 12p in mediastinal germ cell tumor.

The occurrence of an i(12p) in an extragonadal mediastinal germ cell tumor indicates that this chromosome change, which is characteristic for testicular germ cell tumors, can also occur in germ cell tumors present elsewhere in the body. In addition, the karyotype in this patient was near-diploid, in contrast with testicular germ cell tumors, which as a rule are near-triploid or near-tetraploid.

Ketoconazole therapy for advanced prostatic cancer: feasibility and treatment results.

To investigate the feasibility and antitumoral effect of ketoconazole in the treatment of disseminated prostatic cancer, 22 patients with stage D2 disease were treated with 400 mg. ketoconazole orally every 8 hours. Of the 17 patients evaluable for antitumoral effect an initial tumor response of 88 per cent was observed (1 complete and 8 partial responses, and 6 with stable disease) with a mean duration of 15.

Endocrine effects of high-dose ketoconazole therapy in advanced prostatic cancer.

The endocrine effects of ketoconazole (400 mg orally every 8 h) were studied in 9 previously untreated patients with advanced prostatic cancer. Five of these patients were followed for 12 months. A rapid fall in the serum concentration of testosterone was noted in all patients studied.