Calcium Signaling and Molecular Adhesion Processes May Hold the Key to Genetic Risk for Autism: A Molecular Pathway Analysis on Two Independent Samples.

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by limited interests, difficulties in social interactions, repetitive behaviors, and impairments in social communication. ASD tends to run in families, and twin studies suggest a strong genetic basis for the disorder. However, the definition of a genetic profile that indicates a risk for ASD remains unclear.

Using Reinforcement Learning to Develop a Novel Gait for a Bio-Robotic California Sea Lion.

While researchers have made notable progress in bio-inspired swimming robot development, a persistent challenge lies in creating propulsive gaits tailored to these robotic systems. The California sea lion achieves its robust swimming abilities through a careful coordination of foreflippers and body segments. In this paper, reinforcement learning (RL) was used to develop a novel sea lion foreflipper gait for a bio-robotic swimmer using a numerically modelled computational representation of the robot.

Genetic underpinnings of YMRS and MADRS scores variations in a bipolar sample.

Bipolar disorder (BPD) affects approximately 2% of the global population. Its clinical course is highly variable and current treatments are not always effective for all patients. Genetic factors play a significant role in BPD and its treatment, although the genetic background appear to be highly heterogeneous.