Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. More than 200 years after its first clinical description, PD remains a serious affliction that affects a growing proportion of the population. Prevailing treatments only alleviate symptoms; there is still neither a cure that targets the neurodegenerative processes nor therapies that modify the course of the disease.

[Prevalence and complications of gestational diabetes in women followed in Parakou maternities].

Introduction: The study was initiated to determine the prevalence and the complications of gestational diabetes in women attending Parakou maternities clinics in 2015.

Methods: This study was longitudinal, descriptive and analytical. The study population consists of women with gestational diabetes in Parakou maternities wards.

Report of a fatal case of Lassa fever in Parakou in 2018: clinical, therapeutic and diagnostic aspects.

Background: Lassa fever is one of the most lethal neglected tropical diseases in West Africa. It is a serious public health problem in this region of Africa where it is endemic in several countries. However, it remains a very little known disease by healthcare workers.

[Not Available].

This study aims to determine the frequency and identify the factors associated with undernutrition among patients undergoing visceral surgery in 2014. We conducted a cross-sectional, descriptive and analytical study over the period September 11, 2014-December 11, 2014. The study population comprised patients who had undergone visceral surgery at the National University Hospital Centre Koutoucou Hubert MAGA, Cotonou.

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.

Mesodiencephalic dopamine neurons play central roles in the regulation of a wide range of brain functions, including voluntary movement and behavioral processes. These functions are served by distinct subtypes of mesodiencephalic dopamine neurons located in the substantia nigra pars compacta and the ventral tegmental area, which form the nigrostriatal, mesolimbic, and mesocortical pathways. Until now, mechanisms involved in dopaminergic circuit formation remained largely unknown.