Propagation of Orientation Across Lengthscales in Sheared Self-Assembling Hierarchical Suspensions via Rheo-PLI-SAXS.

Simultaneous rheological, polarized light imaging, and small-angle X-ray scattering experiments (Rheo-PLI-SAXS) are developed, thereby providing unprecedented level of insight into the multiscale orientation of hierarchical systems in simple shear. Notably, it is observed that mesoscale alignment in the flow direction does not develop simultaneously across nano-micro lengthscales in sheared suspensions of rod-like chiral-nematic (meso) phase forming cellulose nanocrystals. Rather, with increasing shear rate, orientation is observed first at mesoscale and then extends to the nanoscale, with influencing factors being the aggregation state of the hierarchy and concentration.

Forging out-of-equilibrium supramolecular gels.

The design of supramolecular hydrogels comprising aligned domains is important for the fabrication of biomimetic materials and applications in optoelectronics. One way to access such materials is by the self-assembly of small molecules into long fibres, which can be aligned using an external stimulus. Out-of-equilibrium supramolecular gels can also be designed, where pre-programmed changes of state can be induced by the addition of chemical fuels.

The "gut" corona at the surface of nanoparticles is dependent on exposure to bile salts and phospholipids.

Hypothesis: The formation of a biomolecular corona on nanoparticle surfaces significantly influences their biological behaviour, particularly in drug delivery applications. Despite the prevalence of ingestion of particles (e.g, during oral drug delivery), our understanding of corona formation within the gastrointestinal (GI) tract remains limited, especially for non-protein components.

"I Felt Supported, Empowered, and Encouraged": Early Findings from a Community Initiative to Strengthen and Support Families Through the First 1,000 Days of Life.

Purpose: Evaluation of the First 1,000 Days Suncoast Family Navigation program aimed to (1) describe the social needs of families in Southwest Florida and (2) measure the program's impact on client-reported mental health and social support outcomes.

Design: A multi-method design was employed, including quantitative data collected through an online social care referral network and longitudinal surveys, supplemented by qualitative key informant interview data.

Methods: A convenience sample of 538 parents who submitted online assistance request forms to First 1,000 Days between August 2020 and January 2024 were included.