The Role of High Triglycerides Level in Predicting Cognitive Impairment: A Review of Current Evidence.

The burden of cognitive disorders is huge and still growing, however the etiology and the degree of cognitive impairment vary considerably. Neurodegenerative and vascular mechanisms were most frequently assessed in patients with dementia. Recent studies have shown the possible involvement of triglycerides levels in cognitive function through putative mechanisms such as brain blood barrier dysfunction or amyloid metabolism imbalance, but not all research in the field found this association.

A clinical, epidemiological and laboratory study on avoiding the risk of transmitting viral hepatitis during vaccinations with the Dermojet protected by an anticontaminant disposable device.

Jet injectors may transmit blood-borne infections, such as hepatitis B virus (HBV) and human immunodeficiency virus (HIV). To evaluate the safety of an anticontaminant disposable device which protects the jet injector apparatus, 22,714 healthy subjects were intradermally inoculated (38,162 inoculations) with a variety of vaccines. All the subjects were systematically followed-up clinically and epidemiologically for 6-18 months after inoculation; blood samples from 1619 subjects, before and 60-75 days after inoculation, were examined by enzyme-linked immunosorbent assay (ELISA) for HBV, hepatitis C virus (HCV) and HIV.

Experimental study of the mixed (oral-intradermal) vaccination method in enteric diseases.

Enteric vaccines are currently administered in man either orally or parenterally, each vaccination route having its advantages and disadvantages. In an attempt to cumulate the favourable effects of the two immunization methods a combined (oral-intradermal) anti-S.typhimurium and anti-S.

Experimental study upon the efficacy of some accelerated vaccination schedules in tetanus prophylaxis.

In an attempt to accelerate the antitetanic vaccine-induced immune response necessary particularly in subjects with tetanigenic wounds, groups of guinea pigs or rabbits were i.d. or s.

Experimental study on intradermal antitetanus antityphoid immunization.

A new type of concentrated unadsorbed Tetanus vaccine was administered in animals by intradermal route, associated or not with Typhoid vaccine. The results of the laboratory tests demonstrated that this vaccine is innocuous and produces minimal reactions. A single doses of Tetanus vaccine inoculated in guinea pig or rabbit resulted in a relevant titer which increased when the Typhoid vaccine was associated.