Publications by authors named "A Diederichsen"
Introduction: Myocardial dysfunction and the presence of calcified and non-calcified coronary plaques are predictors of cardiovascular disease. Masculinizing gender-affirming hormone therapy may increase cardiovascular risk, highlighting the need for prospective studies to evaluate cardiovascular outcomes during gender-affirming hormone therapy.
Objectives: To evaluate changes in cardiac morphology, systolic and diastolic function, and development of coronary plaques after masculinizing gender-affirming hormone therapy.
Background: Prospective data on the clinical course of the ascending thoracic aorta are lacking.
Objectives: This study sought to estimate growth rates of the ascending aorta and to evaluate occurrences of adverse aortic events (AAEs)-that is, thoracic aortic ruptures, type A aortic dissections, and thoracic aortic-related deaths.
Methods: In this prospective cohort study from the population-based, multicenter, randomized DANCAVAS (Danish Cardiovascular Screening trials) I and II, participants underwent cardiovascular risk assessments including electrocardiogram-gated, noncontrast computed tomography (CT) scans.
Objective: This study aimed to develop a prediction tool to identify abdominal aortic aneurysms (AAAs) at increased risk of rupture incorporating demographic, clinical, imaging, and medication data using artificial intelligence (AI).
Design: A development and validation study for individual prognosis using AI in a case-control design.
Methods: From two Danish hospitals, all available ruptured AAA cases between January 2009 and December 2016 were included in a ratio of 1:2 with elective surgery controls.
Background: The relationship between environmental pollutants, specifically air pollution and noise, and cardiovascular disease is well-recognized. However, their combined effects on cardiovascular health are not fully explored.
Objectives: To review evidence on the correlation between air pollution and noise exposure and cardiovascular disease incidence and mortality.
Article Synopsis
- The study compares the effectiveness of the CAC-score and 19 biomarkers in predicting cardiovascular disease (CVD) risk, suggesting the CAC-score adds value beyond traditional risk factors.
- Researchers collected data from 1211 participants and tracked cardiovascular events over 10 years, finding a significant association between higher CAC-scores and increased risk of CVD events.
- While the CAC-score improved risk prediction significantly, the selected biomarkers (like cholesterol and inflammatory markers) did not enhance the predictive capacity for cardiovascular events.