Changes in sex and non-sex hormones and distribution of erythrocyte antigens in reproductive age women with tumors of body of uterus in Adjara.

The aim the research was to study the hormonal state of reproductive age women with tumors of body of uterus. The quantitative changes of sex steroid hormones: progesterone (P), estradiol (E), testosterone (T), gonadotropine -Luteinizing hormone (LH) and Follicle-stimulating hormone (FSH) were investigated. Distribution of ABO blood group antigens and Rh-Hr systems genetic variants in the blood of women living in Adjara Region was also studied.

Frequencies of erythrocyte blood groups alleles and haplotyphes in women with benign tumors of the uterus.

The erythrocyte blood groups antigens are associated with risk of certain malignancies though the correlation between blood groups and diseases is still unclear. The investigation is aimed at determining the correlation between benign tumors of the uterus and erythrocyte blood groups alleles and haplotyphes in patients of Adjara Oncology Centre. Blood of 60 women with benign tumors of the uterus and of 60 healthy women of reproductive age were investigated for ABO and Rh system alleles and haplotypes.

Distribution of erythrocyte phenotypic groups in women with benign tumors of the uterus in Adjara Oncology Centre.

ABO blood groups antigens have biological and clinical significance. The ABO blood groups antigens has been associated with many diseases, though the explanation between ABO blood groups and disease is still unclear. The aim of this study is to investigate the presence of a possible association between benign tumors of the utesus with blood ABO, RhD, Kell and MN groups in women in reproductive periods.

Erythrocyte group antigens and women's reproductive system organs.

The aim of this study is to investigate the presence of a possible association between breast and uterus cancer with blood ABO groups in women of reproductive, menopausal and post-menopausal age. Following information was recorded: patient age, stage of cancer, ABO blood group. In diseased population (120 subject) was investigated for ABO red cell blood groups antigens.

Composition of erythrocytic (ABO, Rh-Hr, Kell, MN) group antigens characteristic of the Ozurgeti district's population.

Erythrocytic group antigens represent a genetically stably determined trait. Investigation of antigens of the said system in different regions is of the greatest importance in terms of both the creation of demographic data of the region as well as practical medicine, especially for transplantology and transfusiology. The peripheral or venous blood of 232 local natives (healthy donors) of Ozurgeti district of Guria region has been taken as the test subject.