First Report of the Thermophilic (Linnaeus, 1758) on the Central Adriatic Coast of Italy, in Abruzzo.

The Trabocchi Coast in the Chieti district of the mid-Adriatic (Italy) is one of the few rocky areas within the General Fisheries Commission GSA 17, alongside Mount Conero (Ancona 43°00'01″ N 13°52'13″ E) and the small San Nicola Rock (Ascoli Piceno; 43°32'0″ N 13°36'0″ E). This coastline is known for its biodiversity-rich bays, inlets, and submerged cliffs. Since 2015, annual biodiversity surveys have been conducted in the area, focusing on marine species richness and the identification of non-native species.

Long-Term Ecosystem Monitoring Along the Trabocchi Coast (Chieti, Italy): Insights from Underwater Visual Surveys (2011-2024).

Biodiversity studies are essential for evaluating environmental quality and ecosystem integrity [...

The Synergistic Combination of Curcumin and Polydatin Improves Temozolomide Efficacy on Glioblastoma Cells.

Glioblastoma (GBL) is one of the more malignant primary brain tumors; it is currently treated by a multimodality strategy including surgery, and radio- and chemotherapy, mainly consisting of temozolomide (TMZ)-based chemotherapy. Tumor relapse often occurs due to the establishment of TMZ resistance, with a patient median survival time of <2 years. The identification of natural molecules with strong anti-tumor activity led to the combination of these compounds with conventional chemotherapeutic agents, developing protocols for integrated anticancer therapies.

The RNA from Pseudomonas aeruginosa Reduces Neutrophil Responses Favoring Bacterial Survival.

Introduction: Epithelial and endothelial cells modulate innate immune responses in the lung, including the arrival of neutrophils (PMN), which are crucial cells for the antibacterial host defense. Cells are exposed to prokaryotic RNA (pRNA) during bacterial infections and different pRNA may promote or attenuate the inflammatory response on different immune cells. Pseudomonas aeruginosa (PAE) can cause severe pneumonia and has several immune-evading mechanisms.

Beyond its preferential niche: Brucella abortus RNA down-modulates the IFN-γ-induced MHC-I expression in epithelial and endothelial cells.

Brucella abortus (Ba) is a pathogen that survives inside macrophages. Despite being its preferential niche, Ba infects other cells, as shown by the multiple signs and symptoms humans present. This pathogen can evade our immune system.