Publications by authors named "A Di Benedetto"
Optical aberrations hinder fluorescence microscopy of thick samples, reducing image signal, contrast, and resolution. Here we introduce a deep learning-based strategy for aberration compensation, improving image quality without slowing image acquisition, applying additional dose, or introducing more optics. Our method (i) introduces synthetic aberrations to images acquired on the shallow side of image stacks, making them resemble those acquired deeper into the volume and (ii) trains neural networks to reverse the effect of these aberrations.
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- Global fish and seafood consumption is rising, leading to increased incidents of food fraud, particularly through mislabeling and the use of unauthorized additives to conceal spoilage.
- The study tested two affordable and portable near infrared (NIR) spectrometers to detect the food additive Cafodos in sea bass samples, successfully classifying 81-100% of treated samples.
- The research demonstrates that using portable NIR spectroscopy is a cost-effective and environmentally safe way to quickly identify food fraud and protect consumer safety.
Article Synopsis
- Atopic dermatitis (AD) is an inflammatory skin condition linked to varying levels of Staphylococcus aureus, which affects disease severity and responds to treatments like dupilumab.
- This study aimed to identify host genes related to S aureus levels and AD severity using data from a clinical trial involving 71 adults with moderate-to-severe AD.
- The findings revealed a positive correlation between CERS1 expression (a gene associated with skin lipids) and both S aureus abundance and AD severity, suggesting CERS1 could serve as a biomarker for skin barrier dysfunction, with changes observable after dupilumab treatment.
This study aimed to determine whether a polyphenol-rich cranberry beverage affects skin properties, lipids, and the microbiome in women using a randomized, double-blinded, placebo-controlled, cross-over design. Twenty-two women with Fitzpatrick skin types 2-3 were randomized to drink a cranberry beverage or placebo for six weeks. After a 21-day washout, they consumed the opposite beverage for six weeks.
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- Nodular scleroderma is a rare form of systemic sclerosis marked by hard, fleshy nodules mainly on arms, legs, and trunk, and is often confused with keloid variants, though distinctions have been made recently.
- It typically appears alongside other systemic sclerosis symptoms, especially in individuals with the diffuse systemic sclerosis phenotype, and presents early during skin changes.
- Patients usually have specific antinuclear antibodies but show a low incidence of pulmonary hypertension, with standard treatments not effectively reducing the nodules.