Publications by authors named "A Dezi"

Background: Level of lymph nodes dissection (LND) and inferior mesenteric artery (IMA) ligation is still matter of debate of radical resection of colorectal cancer. This study aims to compare the short-term outcome of three different surgical techniques to treat sigmoid cancer: low ligation (LL) of the IMA with D3-LND, low IMA ligation with D2-LND, and high ligation (HL) of the IMA with D3-LND.

Methods: Patients affected by sigmoid colon cancer, who underwent radical resection with three different techniques (LL and D3-LND Group A, HL and D3-LND Group B, and LL with D2 LND- Group C), were included.

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  • Previous studies have shown that some human populations mixed with extinct species, influencing their ability to adapt to different environmental challenges through a process known as adaptive introgression.
  • A key example involves a gene that helps Himalayan highlanders resist chronic mountain sickness, which was passed down from Denisovans through this gene flow.
  • This research used advanced genetic analysis methods to identify multiple genes that have contributed to specific adaptations in Tibetan and Sherpa populations, particularly in their capacity to manage low oxygen levels at high altitudes.
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  • Minimally invasive surgery for colon and rectal cancer is becoming popular due to benefits like less pain, shorter hospital stays, and faster recovery.
  • The study evaluates the Da Vinci Single-Port (SP) robotic system's safety and outcomes by reviewing 22 studies involving 465 patients, most of whom had a cancer diagnosis.
  • Results showed a median surgery time of 225 minutes with low conversion rates to multi-port methods and overall promising safety, achieving negative margin status in 95% of cases despite some complications.
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  • A multicenter study by the Italian Society of Colorectal Surgery examined treatment trends for anal fissures (AF) over a decade, focusing on various treatment approaches based on AF presentation and sphincter function.
  • Data from 22,016 patients showed significant variability in treatment methods influenced by factors like symptom duration and surgeon preference, with conservative treatments being the most common.
  • The study emphasizes the evolving nature of AF management and calls for more research to identify the best treatment strategies for improved patient outcomes.
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  • Liraglutide, a medication used for obesity treatment, has demonstrated effectiveness in preparing patients for laparoscopic sleeve gastrectomy (LSG), but is linked to gastrointestinal issues like subclinical pancreatitis.
  • A study reviewed the outcomes of 180 patients who underwent LSG, comparing those who used liraglutide preoperatively with those who did not, focusing on operative time, intraoperative adhesions, and post-operative complications.
  • Results indicated that liraglutide-treated patients had lower weight and BMI but a significantly higher rate of intraoperative adhesions (37% vs. 10%), while there were no notable differences in post-operative complications between the two groups.
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