Are Households Affected by Intimate Partner Violence Less Likely to Enroll Children into Early Education in India: Findings from the Fifth National Family Health Survey, 2019 to 2021.

Studies largely from high-income countries show that children exposed to intimate partner violence (IPV) face potential adverse health and developmental outcomes. Limited research has focused on whether IPV exposure affects children's early education participation, particularly in low- and middle-income countries where early education is gaining traction. This study examines whether young children aged 3 to 5 years, living in households affected by IPV, are less likely to be enrolled in school using nationally representative data from India.

Impact of Australia's No Jab, No Pay policy on vaccination uptake - a before-after study in two national birth cohorts.

Background: Data on impact of financial penalties for non-vaccination are sparse. Australia has required full vaccination for government family assistance payment eligibility since 1998. In 2016, the No Jab, No Pay (NJNP) policy removed registered non-medical objection as exemption option and increased eligibility assessment to yearly.

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling.

RHIM is a protein motif facilitating the assembly of large signaling complexes triggering regulated cell death. A few DNA viruses employ viral RHIMs mimicking host RHIMs and counteract cell death by interacting with host RHIM-proteins to alleviate antiviral defenses. Whether RNA viruses operate such viral RHIMs remains unknown.

Rapid and scalable ruthenium catalyzed meta-C-H alkylation enabled by resonant acoustic mixing.

Synthetic chemistry approaches for direct C-H bond alkylation offers a promising alternative to traditional functional-group-centered strategies which often involve multi-step procedures and may suffer from a variety of challenges including scalability. Here, we introduce resonant mixing as an efficient method for meta-C-H alkylation of arenes using a Ru-catalyst, avoiding the need for bulk solvents, external temperature, or light. The described methodology is highly rapid, enabling multigram-scale synthesis of meta-alkylation products within a short reaction time and achieving a very high turnover frequency.

Transition paths across the EMT landscape are dictated by network logic.

During development and cancer metastasis, cells transition reversibly from epithelial to mesenchymal via intermediate cell states during epithelial-mesenchymal transition (EMT). EMT is controlled by gene regulatory networks (GRNs) and can be described by a three-node GRN that permits tristable EMT landscapes. In this GRN, multiple inputs regulate the transcription factor ZEB that induces EMT.