The ability of the prognostic nutritional index to predict short-term mortality in geriatric acute heart failure.

Background: Heart failure is a critical cardiovascular condition, necessitating comprehensive treatment approaches and contributing to elevated mortality rates. This study aimed to evaluate the effect of the prognostic nutritional index (PNI) on the prognosis of geriatric patients diagnosed with acute heart failure.

Results: A total of 104 patients were included and evaluated retrospectively in this study; 57.

Inflammatory Bowel Disease Drivers Revealed in Human Organ Chips.

Inflammatory bowel disease (IBD) patients exhibit compromised intestinal barrier function and decreased mucus accumulation, as well as increased inflammation, fibrosis, and cancer risk, with symptoms often being exacerbated in women during pregnancy. Here, we show that these IBD hallmarks can be replicated using human Organ Chips lined by IBD patient-derived colon epithelial cells interfaced with matched fibroblasts cultured under flow. Use of heterotypic tissue recombinants revealed that IBD fibroblasts are the primary drivers of multiple IBD symptoms.

The PSR corpus: A Persian sentence reading corpus of eye movements.

The present study introduces the Persian Sentence Reading (PSR) Corpus, aiming to expand empirical data for Persian, an under-investigated language in research on oculomotor control in reading. Reading research has largely focused on Latin script languages with a left-to-right reading direction. However, languages with different reading directions, such as right-to-left and top-to-bottom, and particularly Persian script-based languages like Farsi and Dari, have remained understudied.