Publications by authors named "A Desiderio"
The adipose tissue (AT) surrounding breast cancer (BC) plays a pivotal role in cancer progression and represents an optimal source for new biomarker discovery. The aim of this work was to investigate whether specific AT factors may have prognostic value in estrogen receptor-positive (ER+) BC. Proteoglycan Versican (VCAN), Insulin-like Growth Factor 1 (IGF1), Reticulon 4B (RTN4), chemokines CCL5 (also known as RANTES) and interleukin 8 (IL-8) are expressed in AT and may play important roles in BC progression.
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- * Researchers identified PANDAR, a long non-coding RNA (lncRNA), as significantly up-regulated in APCs of individuals with obesity, particularly those transitioning from normal glucose tolerance to impaired glucose tolerance or T2D.
- * Silencing PANDAR in senescent APCs appears to reverse senescence and enable cell cycle re-entry, suggesting that targeting PANDAR may offer a new approach to prevent or delay the progression toward T2D in obese patients.
Article Synopsis
- Cardiac arrest (CA) is a critical condition, and survivors often experience post-cardiac arrest syndrome (PCAS), making echocardiograms essential for evaluating their condition.
- The study reviews existing literature to highlight the significance of transthoracic and transesophageal echocardiograms during and after cardiac arrest.
- The conclusion emphasizes that these echocardiogram techniques play crucial roles in diagnosing and predicting outcomes for patients during the CA phase and beyond.
The cognitive process of opinion formation is often characterized by stubbornness or resistance of agents to changes of opinion. To capture this feature we introduce a constant latency time in the standard voter model of opinion dynamics: after switching opinion, an agent must keep it for a while. This seemingly simple modification drastically changes the stochastic diffusive behavior of the original model, leading to deterministic dynamical oscillations in the average opinion of the agents.
View Article and Find Full Text PDFBackground: Cardiovascular diseases (CVD) affect over half a billion people worldwide and are the leading cause of global deaths. In particular, due to population aging and worldwide spreading of risk factors, the prevalence of heart failure (HF) is also increasing. HF accounts for approximately 36% of all CVD-related deaths and stands as the foremost cause of hospitalization.
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