Publications by authors named "A Derk-Jan ten Harkel"
Background: Prenatal development of autonomic innervation of sinus venosus-related structures might be related to atrial arrhythmias later in life. Most of the pioneering studies providing embryological background are conducted in animal models. To date, a detailed comparison with the human cardiac autonomic nervous system (cANS) is lacking.
View Article and Find Full Text PDFBackground: Cardiopulmonary exercise testing (CPET) has an important prognostic value in adults with different congenital heart defects (CHDs) and is a useful tool for risk stratification and clinical decision-making. In this retrospective study, we studied the prognostic value of CPET in paediatric patients with CHD.
Methods: 411 CPET performed by paediatric patients with different CHDs were evaluated in this retrospective study.
Background: Left ventricular apical pacing (LVAP) is considered to preserve left ventricular (LV) systolic function in both patients with and without congenital heart disease. However, sporadic LVAP-associated cardiac dysfunction in children with complex structural heart disease was recently reported. We present the case of a 2.
View Article and Find Full Text PDFArticle Synopsis
- Fetuses with congenital heart defects (CHD) experience neurodevelopmental delays and complications related to fetal growth and the placenta, which may be linked to placental factors.
- This study compares placental development in CHD cases with differing aortic oxygenation and flow to healthy controls, focusing on the impact of placental conditions on fetal development.
- Results indicate more severe placental issues and fetal complications in CHD cases, with no significant differences between those with reduced oxygenation and reduced flow; suggesting that placental development may have a greater influence on neurodevelopment than fetal blood flow.
Organisation of paediatric echocardiography laboratories and governance of echocardiography services and training in Europe: current status, disparities and potential solutions. A survey from the Association for European Paediatric and Congenital Cardiology (AEPC) imaging working group - CORRIGENDUM.
Cardiol Young
May 2024