Publications by authors named "A Denisenko"
Introduction: Hidradenitis suppurativa (HS) is a prevalent and persistent inflammatory skin disorder, lacking a known cure or effective biomarkers for early diagnosis at present. The genetic determinants of HS have not been fully documented, but it is believed to result from a combination of genetic and environmental factors.
Methods: To identify relevant HS gene variants in sporadic HS patients, this study utilized longitudinal electronic health records (EHRs) and whole-exome sequencing.
Article Synopsis
- We developed a new ambient scanning probe microscope (SPM) that works well with advanced quantum sensing technology using nitrogen-vacancy (NV) centers in diamond.
- The SPM features a qPlus-type tuning fork sensor for high precision, achieving atomic resolution for scanning tunneling microscopy and excellent resolution in atomic force microscopy.
- This system allows for direct imaging of nanoscale targets and enhances the sensitivity of NV centers, paving the way for integrating quantum technologies with nanoscale precision.
Nitrogen vacancy (NV) center-based magnetometry has been proven to be a versatile sensor for various classes of magnetic materials in broad temperature and frequency ranges. Here, we use the longitudinal relaxation time of single NV centers to investigate the spin dynamics of nanometer-thin flakes of α-RuCl at room temperature. We observe a significant reduction in the in the presence of α-RuCl in the proximity of NVs, which we attribute to paramagnetic spin noise confined in the 2D hexagonal planes.
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- Erectile dysfunction (ED) is a common problem for men, and some need surgery with a device called a penile prosthesis (PP) when other treatments don't work.
- A new rabbit model was created to test this device and see how to prevent infections, which is a big concern after the surgery.
- The study found that no recent animal models had used a working PP, so this rabbit model can help researchers explore new ways to reduce infection risks before using these devices in people.
The constant interplay and information exchange between cells and the microenvironment are essential to their survival and ability to execute biological functions. To date, a few leading technologies such as traction force microscopy, optical/magnetic tweezers, and molecular tension-based fluorescence microscopy are broadly used in measuring cellular forces. However, the considerable limitations, regarding the sensitivity and ambiguities in data interpretation, are hindering our thorough understanding of mechanobiology.
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