Publications by authors named "A Delluc"
Background: Angioedema (AE) due to acquired C1-inhibitor deficiency (AAE-C1-INH) is a rare disease associating recurrent edema of mucosa and skin. Several underlying diseases have been reported, mainly lymphoproliferative diseases and monoclonal gammopathy. However, 15 to 20% of patients never exhibit such a hematological condition.
View Article and Find Full Text PDFBackground: Chimeric antigen receptor (CAR) engineered NK cells (CAR-NK) are a novel approach to the immunotherapy of hematologic malignancies which seeks to overcome some of the challenges faced by CAR-T cells (CAR-T). With few published clinical studies, preclinical studies can identify strategies to accelerate clinical translation. We conducted a systematic review on the preclinical in vivo use of CAR-NK for the treatment of hematologic malignancies to assess these therapies in a holistic and unbiased manner.
View Article and Find Full Text PDFIntroduction: Outpatient management of pulmonary embolism (PE) remains controversial in patients with cancer due to their higher risks of mortality, recurrent venous thromboembolism (VTE) and bleeding complications. This systematic review and meta-analysis aimed to evaluate the safety and feasibility of outpatient management of cancer-associated PE.
Methods: We searched MEDLINE, Embase, Cochrane Central, and Scopus databases from inception to May 30, 2024, for studies on outpatient management of cancer-associated PE.
Article Synopsis
- Limited language proficiency significantly impacts research participation among racialized populations, particularly in studies related to venous thromboembolism (VTE).
- An analysis of VTE studies from 2014 to 2024 found that 3.2 out of every 100 eligible patients were unable to consent due to language barriers, with the highest rates observed among cancer studies (5.6) and those recruiting from non-clinic settings (10.8).
- The findings underscore the urgent need for targeted interventions to address linguistic barriers and enhance equitable access to VTE research for underrepresented groups.
Background: Post-thrombotic syndrome (PTS) is common in patients with deep vein thrombosis (DVT). It is unclear if different types of anticoagulant therapies (e.g.
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