Publications by authors named "A Delli Poggi"
Article Synopsis
- Insulin resistance is a crucial factor in developing cardiometabolic diseases, and while genetic risk scores for it have been validated in adults, their applicability to youth is uncertain.
- A study involving children and adolescents with and without obesity evaluated adult-derived genetic risk scores (GRSs) for insulin resistance, showing significant associations with various cardiometabolic traits.
- The findings indicate that these GRSs could help assess insulin resistance-related cardiometabolic risk in youth if further validated in future studies.
Article Synopsis
- This study investigated how TNF-α inhibitor adalimumab affects inflammation and mitochondrial function in adipose tissue in patients with hidradenitis suppurativa (HS) after 12 weeks of treatment.
- Findings showed that while patients had a greater presence of anti-inflammatory macrophages, treatment did not significantly change overall adipose tissue inflammation or mitochondrial respiration.
- Additionally, patients experienced improved quality of life scores, even though clinical symptoms remained unchanged.
: Cardiac arrests are traditionally classified according to the setting in which they occur, including out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). However, cardiac arrests that occur in the emergency department (EDCA) could constitute a third category, due to the peculiar characteristics of the emergency department (ED). In recent years, the need to study EDCAs separately from other intra-hospital events has emerged.
View Article and Find Full Text PDFNontechnical skills (hereinafter referred to as NTS), such as task management, leadership, situational awareness, communication, and decision making contribute to safe and efficient team performance. The importance during cardiopulmonary resuscitation is being increasingly emphasized. We carried out the intercultural adaptation of the TEAM score in Italian and to evaluate the reliability and validity of the resulting Italian version (i-TEAM).
View Article and Find Full Text PDFArticle Synopsis
- * Targeted therapies, particularly those that inhibit the epidermal growth factor receptor (EGFR) pathway using antibodies like Cetuximab and Panitumumab, have been developed, but the effectiveness is often diminished due to drug resistance.
- * Ongoing research includes the use of anti-EGFR antibody-drug conjugates to combat resistance and enhance immune response, along with patient-derived CRC organoids to study treatment responses and tumor heterogeneity effectively.