Publications by authors named "A Della Corte"
Clinical cases referring to the EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ aim to assist physicians in selecting the best management strategies for individual patients with a given condition. These expert opinions consider the impact on patient outcomes as well as the risk-benefit ratio of different diagnostic or therapeutic methods. These cases serve as a vital tool to aid physicians in making decisions in their daily practice.
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- A Loeys-Dietz syndrome patient underwent mitral valve repair and replacement of the aortic root and valve, revealing a previously misdiagnosed Morgagni hernia during a preoperative CT scan.
- The Morgagni hernia was found to contain omentum and was compressing the right ventricle, complicating the patient’s condition.
- Intraoperative observations revealed abnormal blood flow back into the left ventricle, later attributed to major aorto-pulmonary collateral arteries, highlighting the need to consider these congenital features in diagnosis and surgical treatment.
Background: Circulating histones are released by extensive tissue injury or cell death and play important pathogenic roles in critical illnesses. Their interaction with circulating plasma components and the potential roles in the clinical setting are not fully understood.
Objectives: We aimed to characterize the interaction of histones with fibrinogen and explore its roles in vitro, in vivo, and in patient samples.