Publications by authors named "A Degremont"

Introduction: People with epilepsy present an excess risk of mortality, but questions remain regarding the underlying causes and risk distribution. Here, we estimated the excess mortality by age and sex among adults and adolescents with epilepsy in France and identified their main causes.

Methods: A national cohort study was conducted between 2009 and 2019, with adults and adolescents aged between 12 and 60 years and having at least one hospitalization, assurance record, or delivery of anti-seizure medication linked to epilepsy on the French National Health Data System (SNDS).

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Objectives: The primary aim is to assess current lower extremity MRI requests' relevance with a secondary focus on the knee.

Materials And Methods: Using data from the National Health Data System (SNDS), we conducted an observational study of adults (18+) who underwent lower extremity MRI between July 1 and December 31, 2021. This study included analyzing medical consultations and imaging procedures (particularly X-rays) in the 6 months before and after the index MRI, as well as medical procedures and hospitalizations related to knee procedures within 6 months post-MRI.

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Article Synopsis
  • A study analyzed the impact of status epilepticus (SE) on in-hospital mortality and costs using a large French health insurance database from 2015 to 2019, focusing on patient demographics, causes, and healthcare expenses.
  • Among 52,487 patients, 21.8% died in the hospital, with increasing mortality risks associated with older age, acute causes, tumors, and multiple comorbidities, while mechanical ventilation also significantly affected mortality.
  • The average cost per SE hospitalization was around €6,517, highlighting a strong correlation between factors leading to higher mortality and increased healthcare costs, indicating a need for further research on long-term implications.
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Real-world data (RWD) bears great promises to improve the quality of care. However, specific infrastructures and methodologies are required to derive robust knowledge and brings innovations to the patient. Drawing upon the national case study of the 32 French regional and university hospitals governance, we highlight key aspects of modern clinical data warehouses (CDWs): governance, transparency, types of data, data reuse, technical tools, documentation, and data quality control processes.

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