The Role of 70-MHz Ultrahigh-Frequency Ultrasound in the Peripheral Nerve Injury.

Aim: High-frequency ultrasound with an 18-MHz probe (18 MHz-HFUS) plays a relevant role in the evaluation of peripheral nerve injury (PNI). Ultrahigh-frequency ultrasound with a 70-MHz probe (70 MHz-UHFUS) offers higher spatial resolution and could allow a better detection of PNI. This study aimed to compare the diagnostic performance of HFUS and UHFUS in PNI detection.

Mechanism of non-competitive inhibition of the SARS-CoV-2 3CL protease dimerization: Therapeutic and clinical promise of the lichen secondary metabolite perlatolinic acid.

In response to the COVID-19 pandemic, identifying effective treatments against SARS-CoV-2 has become of utmost importance. This study elucidates the mechanism by which perlatolinic acid, a lichen-derived secondary metabolite, non-competitively inhibits the dimerization of the SARS-CoV-2 3CL protease, a pivotal enzyme in the virus lifecycle. Utilising a combination of kinetic parameter determination, inhibition assays, and molecular docking studies, we demonstrate that perlatolinic acid effectively disrupts the enzymatic function by binding at the dimer interface with a measured value of 0.

Amblyomma sparsum Neumann 1899 on migratory birds from Africa: First records in Italy.

Migratory birds play an important role in transporting ixodid ticks and tick-borne pathogens between continents. During the Boreal spring, migratory birds reach Europe, mainly from sub-Saharan Africa or from northern African countries but not much is known about the diversity and ecology of the ticks they spread. From 2017 to 2022, in the framework of two consecutive projects focused on sampling migratory birds from Africa to Europe, a total of 27 immature Amblyomma ticks were collected from migratory birds, belonging to 8 species, captured on the Island of Ventotene, an important stop-over site in the Mediterranean Sea.

Taxonomic considerations of selected Western Palaearctic Mordellidae Latreille, 1802 (Coleoptera, Tenebrionoidea).

The present contribution is devoted to the review of some species of Mordellidae belonging to the Italian fauna described by Mariano Zuccarello Patti and Mario Enrico Franciscolo. New taxonomic combinations are proposed: (Franciscolo, 1942), , Franciscolo, 1942, , and Franciscolo, 1942, , and are considered species that are not part of the Italian fauna. In addition, given the impossibility of identifying the species based on its original description and the destruction of type material, Patti, 1840 is treated as .