Mild Gestational Hypothyroidism in Mice Has Transient Developmental Effects and Long-Term Consequences on Neuroendocrine Systems.

Thyroid hormones (TH) play a key role in fetal brain development. While severe thyroid dysfunction, has been shown to cause neurodevelopmental and reproductive disorders, the rising levels of TH-disruptors in the environment in the past few decades have increased the need to assess effects of subclinical (mild) TH insufficiency during gestation. Since embryos do not produce their own TH before mid-gestation, early development processes rely on maternal production.

Small Bowel Obstruction Caused by Obturator Hernia.

In an elderly patient with a history of atypical, intermittent medial thigh pain presenting with signs of intestinal obstruction, entrapment of bowel loops in an obturator hernia should be included in the differential diagnosis and should be further elaborated by computed tomography (CT).

Towards atom counting from first moment STEM images: Methodology and possibilities.

Through a simulation-based study we develop a statistical model-based quantification method for atomic resolution first moment scanning transmission electron microscopy (STEM) images. This method uses the uniformly weighted least squares estimator to determine the unknown structure parameters of the images and to isolate contributions from individual atomic columns. In this way, a quantification of the projected potential per atomic column is achieved.