Publications by authors named "A Davy"
Article Synopsis
- Dimethylsulfoniopropionate (DMSP) is an important organosulfur compound involved in stress protection and the cycling of carbon and sulfur, while also contributing to climate-active gases.
- Saltmarshes, particularly those with Spartina cordgrasses, are key areas for DMSP production, with Spartina anglica showing exceptionally high levels due to specific plant genes.
- The study identifies critical enzymes for DMSP synthesis in Spartina anglica and suggests that increasing DMSP levels can enhance plant resistance to salinity and drought, paving the way for potential bioengineering applications in sustainable agriculture.
Article Synopsis
- Therapeutic antibodies utilize their Fc region to connect with immune mechanisms, particularly through binding to complement proteins and Fc receptors, which is vital for their effectiveness.
- Researchers have engineered various Fc region variants of anti-CD20 antibodies and conducted cell-based assays to evaluate their abilities in processes like complement-dependent and antibody-dependent cytotoxicity.
- The study provided insights into how these antibody variants perform differently, suggesting that certain variants may be better suited for specific therapeutic applications due to their unique activities and thermal stability.
Background And Aims: Crithmum maritimum is a wild, edible halophyte with large potential as a cash crop for salinized soils. However, its tolerance during seed germination appears to be highly site-specific and contradictory, whereas little is known on salinity tolerance during early seedling growth. This study aimed to characterize variation in the responses of germination and early seedling growth in diverse C.
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- Researchers aim to eliminate the binding of immunoglobulin Fc to Fc gamma receptors to prevent unwanted inflammation from therapeutic antibodies and fusion proteins.
- A matched set of anti-CD20 antibodies with various Fc subclasses and variants were created to assess their binding activity to C1q and Fc-gamma receptors, as well as their performance in cell-based assays.
- The findings showed that many variants retained significant activity in at least one assay but often had decreased temperature stability compared to the wild-type antibody.
Aim: Volar locking plates designed for far distal radius fracture fixation can have a significant hardware removal rate and risk of tendon rupture. Plate design has a role in the rate of complications. This study assessed the hardware removal and tendon rupture rate of the Acu-Loc 2 volar distal radius (VDR) plate often used in the treatment of far distal radial fractures.
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