Use of plasma volume substitutes and plasma in developing countries.

Plasma and plasma substitutes are used in the treatment of various conditions such as haemorrhage and shock. This article examines the role of crystalloids, artificial colloids, human plasma, human albumin, and plasma protein fraction, in the treatment of such patients, with particular reference to peripheral health facilities in developing countries.It is concluded that 0.

Spleen weight distribution in Ibadan and its relationship to disease.

The 5407 autopsies performed during an 8-year period formed the basis of the study; 2444 were infants and children, while 2963 were adults. The histogram of the spleen weight distribution has a fairly smooth contour with a positive skew towards the heavier spleens. The mean adult spleen weight was 271 g, and this was heavier than that of subjects in temperate climates, but comparable to the mean spleen weight of other localities in a holoendemic belt of malaria.

The use of lymphocyte transformation and IgM estimation as diagnostic aids in leukaemoid reactions.

Twenty-two patients with lymphocytosis and sometimes accompanied by splenomegaly selected from our difficult diagnostic cases over the past two years are presented. The clinical and laboratory features pointed to one of the following: chronic lymphatic leukaemia without lymphadenopathy, lymphosarcoma or other lymphoreticular tumour, tropical splenomegaly syndrome with a lymphatic leukaemoid reaction. The precise diagnosis was usually made by haemotological laboratory tests - viz.

Frequency of blood group antigens in Nigerian children with falciparum malaria.

The frequencies of the following blood group antigens: A, B, O, M, N, S, s, U, Fya, FyB, Lea, Jsa and K have been determined in Nigerian children with severe falciparum malaria. The frequency distribution of M, N, S, s, U, Fya and Fyb were not significantly different in children with life-threatening falciparum malaria and controls. The frequencies of A, B, O, Lea, Jsa and K found in the children with severe malaria were similar to those previously reported for healthy adults in this population.