Publications by authors named "A Dasmahapatra"

Parabens are the most prevalent ingredients in cosmetics and personal care products (PCPs). They are colorless and tasteless and exhibit good stability when combined with other components. Because of these unique physicochemical properties, they are extensively used as antimicrobial and antifungal agents.

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Article Synopsis
  • Alzheimer's disease (AD) is a leading cause of dementia and death globally, characterized by the harmful accumulation of Aβ fibrils in the brain.
  • The study used molecular dynamics simulations to explore how Baicalein (BCL), a natural flavonoid, destabilizes the amyloid protofibril by disrupting its structural integrity and hydrophobic interactions.
  • Findings suggest that BCL increases the movement of protofibrils and reduces their stability, indicating its potential as a therapeutic agent for AD treatment.
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Japanese medaka () is an acceptable small laboratory fish model for the evaluation and assessment of endocrine-disrupting chemicals (EDCs) found in the environment. In this research, we used this fish as a potential tool for the identification of EDCs that have a significant impact on human health. We conducted an electronic search in PubMed (http://www.

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The datasets of this article present the experimental parameters resulting from the assessment of δ-cells in the islet organs of the endocrine pancreas as a potential biomarker of endocrine disruption (ED) mediated by graphene oxide (GO), using Japanese medaka fish as the model. These datasets support the article "Evaluation of pancreatic δ-cells as a potential target site of graphene oxide toxicity in Japanese medaka () fish". GO used in the experiments was either obtained from a commercial source or synthesized in the laboratory by us.

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The therapeutic strategy employing destabilization of the preformed Aβ fibril by various natural compounds, as studied by experimental and computational methods, has been reported significant in curing Alzheimer's disease (AD). However, lycopene (a carotenoid), from terpenes family, needs investigation for its destabilization potential of Aβ fibril. The highest antioxidant potential and ability to cross blood brain barrier makes lycopene a preferred choice as drug lead for treating AD.

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