Publications by authors named "A Dammermann"
Article Synopsis
- - Centrioles are key structures in centrosomes that help organize cell division by managing the assembly of the mitotic spindle and chromosome separation in animal cells.
- - In sexually reproducing species, centrioles degenerate during female meiosis but are retained and reintroduced during male meiosis and fertilization, while their role in parthenogenetic (asexual) species is less understood.
- - Research shows that in two asexual parthenogenetic nematode species, centrioles are maternally inherited, with different strategies affecting how they organize meiotic spindles and contribute to embryo development, functioning similarly to sperm-derived centrioles in sexually reproducing species.
Cilia are cellular projections that perform sensory and motile functions in eukaryotic cells. A defining feature of cilia is that they are evolutionarily ancient, yet not universally conserved. In this study, we have used the resulting presence and absence pattern in the genomes of diverse eukaryotes to identify a set of 386 human genes associated with cilium assembly or motility.
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- The COVID-19 pandemic hit Germany in early 2020, leading the government to impose strict lockdown measures, including banning visits to nursing homes to protect vulnerable people.
- To understand how nursing homes in Germany managed during this time, researchers interviewed 78 managers from various homes about their experiences and challenges.
- They found both difficulties, like increased stress and communication demands, and some positive outcomes, such as better teamwork and support systems among managers.
Proximity-dependent labeling approaches such as BioID have been a great boon to studies of protein-protein interactions in the context of cytoskeletal structures such as centrosomes which are poorly amenable to traditional biochemical approaches like immunoprecipitation and tandem affinity purification. Yet, these methods have so far not been applied extensively to invertebrate experimental models such as C. elegans given the long labeling times required for the original promiscuous biotin ligase variant BirA*.
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