Publications by authors named "A Dahmen"
Background And Objective: The role of focal therapy in the treatment of localized prostate cancer is evolving. However, despite accumulating evidence, current guidelines and regulatory bodies refrain from endorsing focal therapy outside of clinical trials. Our goal was the to review the focal therapy realm for ongoing clinical trials and high impact recently published trials.
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- The study aimed to evaluate a genomic classifier (GC) to identify a subgroup of bladder cancer patients with a favorable prognosis based on long non-coding RNA (lncRNA) profiles following radical cystectomy (RC).
- Researchers analyzed tumor samples from 226 patients and classified them into subtypes, with a focus on overall survival and cancer-specific mortality as key outcomes.
- Results indicated that patients with the luminal favorable subtype had significantly better survival rates and lower risks of cancer progression compared to others, supporting the GC's effectiveness in assessing tumor aggressiveness.
Purpose: The use of immediate postoperative intravesical chemotherapy (IVC) following transurethral resection of bladder tumor (TURBT) has been shown to reduce the rate of recurrence of nonmuscle invasive bladder cancer. Historically, utilization of IVC following TURBT has been low. We sought to determine the rate of immediate postoperative IVC following TURBT, as well as assess factors that may influence its use.
View Article and Find Full Text PDFObjective: To analyse the management and outcomes of individuals diagnosed with prostate cancer either before or after organ transplantation, as the impact of organ transplantation and associated immunosuppression on the incidence, progression, and mortality of prostate cancer remains an area of substantial clinical interest and uncertainty.
Patients And Methods: We conducted a retrospective analysis of patients from two tertiary care centres who had solid organ transplantation and were diagnosed with prostate cancer before or after organ transplantation. Data collected included demographics and clinical information.
Purpose: Radical cystectomy is a highly morbid procedure with short term perioperative complications rates cited to be as high as 60%. Short term perioperative complications have been demonstrated to be more frequent in underweight and overweight patients. We sought to evaluate the impact of metabolic syndrome on surgical outcomes.
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