Publications by authors named "A D Vladimirova"

Microbial reduction of selenium oxyanions, highly soluble, mobile and toxic inorganic selenium compounds, to insoluble selenium nanoparticles (Se NPs) is a widely spread phenomenon which is of geochemical, environmental and biotechnological importance. While selenite bioreduction is known for a wide variety of microorganisms, selenate bioreduction is not so common and has mostly been documented for anaerobes, with merely a few reported cases related to aerobic or microaerobic conditions. In some biogenic Se NPs of microbial origin, the presence of sulfur was detected together with selenium in Se NPs, particularly when increased concentrations of sulfate were present in the medium.

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Article Synopsis
  • Cancer is complex and expensive to analyze, often requiring genetic profiling for better treatment strategies.
  • Recent advancements in deep learning have improved the prediction of genetic changes from whole slide images, but transformers have been challenging to implement due to their complexity and data limitations.
  • The new SEQUOIA model, which uses a simplified transformer approach, successfully predicts cancer-related gene information from vast numbers of tumor samples and has shown promise in aiding breast cancer risk assessment and understanding gene expression in specific regions.
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Aging is a complex process manifesting at molecular, cellular, organ, and organismal levels. It leads to functional decline, disease, and ultimately death, but the relationship between these fundamental biomedical features remains elusive. By applying elastic net regularization to plasma proteome data of over 50,000 human subjects in the UK Biobank and other cohorts, we report interpretable organ-specific and conventional aging models trained on chronological age, mortality, and longitudinal proteome data.

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Background: Many bacteria are capable of reducing selenium oxyanions, primarily selenite (SeO), in most cases forming selenium(0) nanostructures. The mechanisms of these transformations may vary for different bacterial species and have so far not yet been clarified in detail. Bacteria of the genus , including ubiquitous phytostimulating rhizobacteria, are widely studied and have potential for agricultural biotechnology and bioremediation of excessively seleniferous soils, as they are able to reduce selenite ions.

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