Publications by authors named "A D Shore"
The QUAD nations' (United States, India, Japan, and Australia) financial markets are deeply integrated with global markets. The burgeoning surge of risk in global markets requires caution, which can be possible by determining the connectedness. This study elucidates the dynamic connectedness between crude oil and the financial markets of QUAD nations, aiming to enhance understanding of its environmental and managerial implications.
View Article and Find Full Text PDFContexts and complexities: a realist evaluation of integrated care system leadership.
Leadersh Health Serv (Bradf Engl)
November 2024
Article Synopsis
- This paper evaluates leadership within an integrated care system (ICS) in England, focusing on effective leadership aspects and their contexts post-COVID-19 pandemic.
- Using realist evaluation methodology, the study involved 23 interviews with ICS leaders, observations of meetings, and document analysis to understand the mechanics of successful leadership.
- Key findings highlight the importance of a strong sense of purpose and leadership visibility in enhancing workforce morale, while challenges like financial constraints and differing regulatory environments hinder responsiveness and innovation in addressing health inequalities.
Article Synopsis
- * In mouse studies, a specific GOF variant was examined, revealing that while it did not affect glutamatergic or VIP neurons, it caused SST neurons to become less excitable and PV neurons to become more excitable, both affecting their electrical activity.
- * The functional differences in SST and PV neurons were attributed to an increased persistent sodium current in PV neurons, showing that the pathogenic mechanisms can lead to opposite effects in similar neuron types and highlighting the complexity of treatment approaches for these disorders.
Observational studies indicate that colonization and allergic bronchopulmonary aspergillosis (ABPA) in people with cystic fibrosis (CF) are associated with poorer lung health and increased disease severity. We performed a longitudinal observational cohort study to analyse long-term outcomes of colonization and ABPA in children with CF. Anonymised UK CF Registry data from 2009 to 2019 for patients aged 8-17 years in 2009-2010 were collected.
View Article and Find Full Text PDFObjective: Hypertension is a recognized risk factor for the development of cognitive impairment and dementia in older adults. Aortic stiffness and altered haemodynamics could promote the transmission of detrimental high pressure pulsatility into the cerebral circulation, potentially damaging brain microvasculature and leading to cognitive impairment. We determined whether reservoir-excess pressure parameters were associated with cognitive function in people with hypertension (HT) and normotension (NT).
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