[Immune reaction to anesthesia and surgical injury in neonatal infants].

The impact of surgical injury and anesthesia on cellular and humoral immunity parameters was studied in neonatal infants with surgical pathology. These were found to have immunosuppressive activity, which appeared as evolving absolute lymphopenia and a reduction in the serum concentration of IgG. The magnitude of these changes depends on the functional state of the immune system in the preoperative period and is higher in infants with signs of an infectious-inflammatory process in the preoperative period, which increases the risk of septic complications.

[Non-drug prevention of pain in neonatal infants].

When treated at a hospital unit, full-term and preterm neonatal infants undergo a large number of manipulations and procedures, most of them are rather painful; anesthesia is used inadequately frequently. Pain prevention during procedures is able to reduce a baby's discomfort and to improve his/her tolerance of medical manipulations and care procedures.

[Characteristics of anesthesia in newborn infants].

The paper describes the specific features of anesthetic maintenance in preterm and full-term neonates, intraoperative monitoring, and the effects of inhaled anesthetics, narcotic analgesics, sedatives, and myorelaxants with emphasis on the anatomic and physiological features of a developing organism.