Publications by authors named "A D Sannejal"
Antibiotic resistance and virulence factors in avian pathogenic Escherichia coli (APEC) have become significant concerns, contributing to adverse environmental effects. The extensive use of antibiotics in poultry farming has resulted in the emergence of antibiotic-resistant APEC strains. This study prioritizes the molecular screening of APEC to uncover their antibiotic resistance and virulence attributes, with specific attention to their environmental impact.
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- Pathogenic bacteria pose a major threat to human health but also offer potential therapeutic opportunities for disease prevention and treatment.
- The article discusses virulence determinants, which are elements that help pathogens cause damage to their hosts, and how targeted therapies can be developed to combat these mechanisms.
- It highlights the innovative use of CRISPR-based therapy and antisense RNA (asRNA) as new strategies for selectively disabling the virulence factors in these bacteria, marking the first review to combine both technologies in this context.
The increasing resistance of the disease-causing pathogens to antimicrobial drugs is a public health concern and a socio-economic burden. The emergence of multi-drug resistant strains has made it harder to treat and combat infectious diseases with available conventional antibiotics. There are currently few effective therapeutic regimens for the successful prevention of infections caused by drug-resistant microbes.
View Article and Find Full Text PDFMastitis is one of the most common and burdensome diseases afflicting dairy animals. Among other causes of mastitis, staphylococci are frequently associated with clinical and subclinical mastitis. Although Staphylococcus aureus is the predominant species involved, Staphylococcus epidermidis and other coagulase-negative staphylococci are increasingly being isolated from cases of bovine mastitis.
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