Publications by authors named "A D Rubenstein"
Article Synopsis
- The goal of computational psychiatry is to create models that connect differences in brain function to cognitive impairments and symptoms, which are often resistant to treatment.* -
- Research shows that to predict cognitive functioning accurately, large participant samples are needed, highlighting limitations in smaller patient studies.* -
- Using a transfer learning approach on neuroimaging data from the UK Biobank, the study found that predictions of cognitive functioning improved significantly, even with smaller sample sizes, validating the effectiveness of training models on larger datasets.*
Background: Since 1990, childhood overweight and obesity have been rising on every continent and have almost doubled worldwide. The deleterious consequences include hypertension, type 2 diabetes mellitus, and dyslipidemia leading to metabolic syndrome in childhood and myocardial infarction, stroke, cancer and other disabling conditions in adulthood.
Purpose: In Southern Europe, including Greece, Italy, and Spain, 10 to 15% of children are obese.
Objective: Although treatment of posttraumatic stress disorder (PTSD) is effective in reducing symptom severity, remission rates are low. One potential underlying reason for treatment ineffectiveness is differential response of specific PTSD symptom clusters. Using data from a national Veterans Affairs (VA) residential PTSD treatment cohort, we conducted a longitudinal study to examine changes in PTSD symptom clusters from admission to 1-year follow-up.
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- The study aims to connect brain functioning profiles with symptoms and behaviors in psychiatric patients by introducing a new dataset.
- This dataset includes brain imaging and behavioral data from 241 individuals, with a mix of 148 people diagnosed with psychiatric illnesses and a healthy group of 93.
- It provides a comprehensive resource including high-resolution scans, fMRI data, and over 50 psychological assessments to facilitate research in neuroscience.
We respond to commentaries by Brown (2024) and Najavits (2024) on our original work titled "To Expose or Not to Expose: A Comprehensive Perspective on Treatment for Posttraumatic Stress Disorder" (Rubenstein et al., 2024). Their work serves to augment the original argument that exposure is an important change factor in the amelioration of traumatic stress but should be viewed more broadly than traditional treatment paradigms suggest.
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