Publications by authors named "A D Haddow"
Background: Multimorbidity, the co-existence of two or more conditions within an individual at any one time, is globally increasing and forecasted to rise. This poses a significant challenge for current models of healthcare delivery, which are now ill-equipped to meet the future population health needs. Interprofessional collaborative practice is a specific way professionals work closely together and with patients and their families to improve patient outcomes.
View Article and Find Full Text PDFWe report strong Zika virus (ZIKV) neutralizing antibody responses in African green monkeys (Chlorocebus sabaeus) up to 1,427 days after ZIKV exposure via the subcutaneous, intravaginal, or intrarectal routes. Our results suggest that immunocompetent African green monkeys previously infected with ZIKV are likely protected from reinfection for years, possibly life, and would not contribute to virus amplification during ZIKV epizootics.
View Article and Find Full Text PDFBackground: Lung cancer is the most common cause of cancer death in the UK. Low-dose computed tomography (LDCT) screening has been shown to identify lung cancer at an earlier stage. A risk stratified approach to LDCT referral is recommended.
View Article and Find Full Text PDFArticle Synopsis
- Effective therapies have been created for treating acute Ebola virus disease (EVD), but the long-term effects on survivors, particularly regarding viral persistence, are still uncertain.
- Research on rhesus macaques showed that even after treatment with monoclonal antibodies (mAb), Ebola virus (EBOV) can persist in the brain's ventricular system, leading to severe tissue damage.
- The study emphasizes the need for monitoring potential long-term health issues in human EVD survivors, as the treated macaques experienced fatal infections confined to the brain after initial recovery.