Societal decarbonization is essential for environmental sustainability and prosperity, requiring cohesive efforts to advance materials circularity alongside the development of zero-carbon energy and heat solutions. In most systems, these challenges are addressed separately. However, creating integrated solutions that connect opportunities across energy and materials loops can be transformative and critical for achieving lasting impact.
View Article and Find Full Text PDFAims: Soft-tissue sarcomas (STSs) are rare cancers with centralized care advocated to consolidate resources and expertise. However, geographical challenges, particularly in countries like Canada, can increase travel distances for patients. The impact of travel distance on sarcoma presentation and outcomes remains unclear, particularly in single-payer healthcare systems with centralized care.
View Article and Find Full Text PDFPer- and polyfluoroalkyl substances (PFAS) are an emergent threat to the environment due to their toxic, carcinogenic, and environmentally persistent nature. Commonly, these harmful micropollutants are removed from contaminated water sources through adsorption by porous sorbents such as activated carbon. While studies suggest a relationship between sorbent pore size and their PFAS remediation performance, the underlying mechanisms-particularly those related to sorbate morphology-have not been elucidated through direct experimental observations.
View Article and Find Full Text PDFBackground: Early-onset severe toxicity following the administration of 5-fluorouracil (5-FU) or capecitabine occurs in approximately 10-30% of patients receiving fluoropyrimidine therapy in the USA and is fatal to at least 0.5% of patients treated. Supportive care measures used to manage symptoms of toxicity are associated with extended hospital length of stay, high cost of care, and poor survival.
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