Background: The embryonic definitive endoderm (DE) gives rise to organs of the gastrointestinal and respiratory tract including the liver, pancreas and epithelia of the lung and colon. Understanding how DE progenitor cells generate these tissues is critical to understanding the cause of visceral organ disorders and cancers, and will ultimately lead to novel therapies including tissue and organ regeneration. However, investigation into the molecular mechanisms of DE differentiation has been hindered by the lack of early DE-specific markers.
View Article and Find Full Text PDFWe analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue.
View Article and Find Full Text PDFThe prompt clearance of a patient's cervical spine is extremely beneficial both to the patients and the department however correct guidelines and education must be established before this can be undertaken safely. This paper examines whether nurses given the appropriate training and education using appropriate diagnostic and clinical criteria can safely, effectively clear cervical spines without consulting a medical practitioner. The paper explores the use of the Nexus Guidelines [J.
View Article and Find Full Text PDFUnlabelled: The purpose of this study was to determine which single-use wound adhesive is the most appropriate in terms of ease of use, minimal pain on application, adequate bonding time and wound closure. The three wound adhesives audited were Indermil (n-butyl cynoacrylate), Liquiband (n-butyl cynoacrylate) and Dermabond (octylcyanoacrylate).
Sample And Setting: The study was conducted in an urban paediatric emergency department treating over 39,000 patients annually.