[Controlled myorelaxation in patients with aldosteroma].

Purpose of the study was to develop techniques of controlled myorelaxation during surgeries in patients with aldosteroma. 46 patients were involved in the study. Adrenalectomy was performed by videoendoscopy from retroperitoneal access.

[Clofelin in the anesthesiological support system for surgical operations].

The article presents clinical experience of using Clofelin in 251 patients as a part of general anaesthesia, in postoperative period and in patients with peripheral vascular disease. The experiments on 14 rabbits chinchilla have been done prior to peridural use of Clofelin. The control for adequate use included estimation of hemodynamics parameters, cortizol, vasopressin and B-endorphin levels in plasma on different anaesthesia.

[Epidural analgesia with clofelin as a component of general anesthesia].

A clinical experience with using peridural analgesia with Clophelin in the composition of general anesthesia in 35 patients operated upon because of surgical, gynecological and urological diseases is presented. Clinical application of Clophelin in anesthesiological maintenance was preceded by an experimental study in rabbits. Control of adequacy of the anesthesia was performed by parameters of central hemodynamics and the level of vasopressin in blood plasma at stages of the research.

[Epidural analgesia with clofelin in treating a pain syndrome].

The article presents a clinical experience with using epidural analgesia with Clofelin in 20 patients to arrest the pain syndrome developed at the postoperative period and resulting from atherosclerotic lesions of the lower extremity vessels. Control of the adequacy of anesthesia was made by registration of the H-reflex value. The investigations have shown that epidural analgesia with Clofelin is an effective measure to arrest the pain syndrome.

[Detoxification in the combined intensive therapy of patients with multiple organ failure].

Studies of the influence of the UV irradiation of autologous blood (UVIAB) and hemosorption (HS) upon changes of indices of endogenous intoxication in patients with the syndrome of polyorganic insufficiency (SPOI) have shown that the isolated (without HS) UVIAB reduces toxemia and prevents the development of SPOI in patients without pronounced alterations of microcirculation. Using the UV irradiation of autoblood in patients with clinically marked alterations of the peripheral blood circulation increases toxemia at the expense of release of toxic products from the "disclosed" system of microcirculation. HS with the simultaneous taking the blood from the subclavian vein and abdominal aorta with using "Actilen" and return of the mixed blood into the peripheral artery interrupts and relieves the course of SPOI.