[Comparison of resting state and task-based functional MRI in preoperative mapping in patients with brain gliomas].

Objective: To analyze and compare the results of cerebral cortex mapping with task-based (tb-fMRI) and resting-state functional MRI in patients with glioma of eloquent cortical areas.

Material And Methods: There were 55 patients (24 men and 31 women aged 24 - 74 years, median 39) with glial tumors. In 26 patients, the tumor was located in motor areas.

[Machine learning for resting state fMRI-based preoperative mapping: comparison with task-based fMRI and direct cortical stimulation].

Objective: To develop a system for preoperative prediction of individual activations of motor and speech areas in patients with brain gliomas using resting state fMRI (rsfMRI), task-based fMRI (tb-fMRI), direct cortical stimulation and machine learning methods.

Material And Methods: Thirty-three patients with gliomas (19 females and 14 males aged 19 - 540) underwent DCS-assisted resection of tumor (19 ones with lesion of motor zones and 14 patients with lesions of speech areas). Awake craniotomy was performed in 14 cases.

[Resting-state fMRI in preoperative non-invasive mapping in patients with left hemisphere glioma].

Maximum resection and preservation of neurological function are main principles in surgery of brain tumors, especially glial neoplasms with diffuse growth. Therefore, exact localizing of eloquent brain areas is an important component in surgical planning ensuring optimal resection with minimal postoperative neurological deficit. Functional MRI is used to localize eloquent brain areas adjacent to the tumor.

Hemorrhagic Fever with Renal Syndrome, Russia.

In Russia, 131,590 cases of hemorrhagic fever with renal syndrome caused by 6 different hantaviruses were reported during 2000-2017. Most cases, 98.4%, were reported in western Russia.

[Variants of the immunoreactivity and infectious process in bank vole (Myodes glareolus) experimentally infected with the hantavirus Puumala (PUUV)].

As a result of a longitudinal study of the Puumala hantavirus (PUUV) in the experimentally infected bank voles (Myodes glareolus), we revealed three groups of the voles differing in the immunoreactivity and viral antigen concentration in the organs. The close correlation between these parameters suggested the existence of various mechanisms of the hantavirus persistence in the host.