Publications by authors named "A D B Vizzotto"
There is no established treatment for patients with clozapine-resistant schizophrenia (CRS). Clozapine augmentation strategies with antipsychotics or others substances are effective in comparison with placebo while and Electroconvulsive therapy (ECT) showed to be effective in comparison with treatment as usual (TAU) but not with placebo (sham-ECT). In the present double- blind randomized controlled trial, we compared 40 outpatients who received 20 sessions of ECT (n = 21) or sham-ECT (n = 19) (age = 37.
View Article and Find Full Text PDFArticle Synopsis
- - Breast cancer is the most common cancer in women in Brazil, with a significant portion (over two-thirds) of patients expressing hormone receptors, making hormone therapy with tamoxifen a common treatment, which can raise the risk of endometrial cancer by four times.
- - This study evaluated 364 breast cancer patients to investigate the link between tamoxifen use and endometrial issues, finding that 7.3% of tamoxifen users experienced endometrial changes, while none in the non-treatment group did.
- - The research concluded that tamoxifen use is significantly associated with endometrial changes, even after accounting for obesity as a risk factor, highlighting the importance of monitoring endometrial health in patients undergoing hormone therapy
Importance: The occupational goal intervention (OGI) method has been proven effective in improving executive function (EF) in people with schizophrenia, but it has not yet been tested with those with treatment-resistant schizophrenia (TRS).
Objective: To test the efficacy of the OGI in people with TRS.
Design: Single-blind randomized controlled trial.
Adjunctive Therapy to Manage Neuropsychiatric Symptoms in Moderate and Severe Dementia: Randomized Clinical Trial Using an Outpatient Version of Tailored Activity Program.
J Alzheimers Dis
December 2021
Background: Neuropsychiatric symptoms (NPS) such as aggression, apathy, agitation, and wandering may occur in up to 90%of dementia cases. International guidelines have suggested that non-pharmacological interventions are as effective as pharmacological treatments, however without the side effects and risks of medications. An occupational therapy method, called Tailored Activity Program (TAP), was developed with the objective to treat NPS in the elderly with dementia and has been shown to be effective.
View Article and Find Full Text PDFBackground: Negative symptoms are a core feature of schizophrenia. The Brief Negative Symptom Scale (BNSS) is a scale developed to measure negative symptoms in schizophrenia.
Methods: The present study aimed to examine the construct validity of BNSS, by using convergent and divergent validities as well as factor analysis, in a Brazilian sample of 111 outpatients diagnosed with schizophrenia by DSM-5.