Publications by authors named "A D'Avino"

Sore throat represents one of the main causes of antibiotic overprescription in children. Its management is still a matter of debate, with countries considering streptococcal pharyngotonsillitis a benign and self-limiting condition and others advocating for its antibiotic treatment to prevent suppurative complications and acute rheumatic fever. Italian paediatricians frequently prescribe antibiotics on a clinical basis regardless of microbiological results.

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  • The combination of paracetamol and ibuprofen is effective for treating mild-to-moderate acute pain in children, particularly for conditions like headaches, earaches, and post-operative pain.
  • A survey of pediatricians showed strong support for the fixed-dose combination, emphasizing its superiority over single-drug therapies and its tolerability among children.
  • Future research is needed to explore its potential benefits for chronic and inflammatory pain conditions in pediatric patients.
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  • * In the study, patients using 5-ASA alone showed clinical response rates of 41% at three months and 60.2% at six months, while those taking 5-ASA with nutraceuticals had higher response rates of 49.6% and 70.4%, respectively; however, the difference in overall response rates was not significant.
  • * Notably, the clinical remission rates and reductions in faecal calprotectin levels were significantly
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Single-cell sequencing has characterized cell state heterogeneity across diverse healthy and malignant tissues. However, the plasticity or heritability of these cell states remains largely unknown. To address this, we introduce PATH (phylogenetic analysis of trait heritability), a framework to quantify cell state heritability versus plasticity and infer cell state transition and proliferation dynamics from single-cell lineage tracing data.

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Plasmonic metasurfaces with spatial symmetry breaking are crucial materials with significant applications in fields such as polarization-controlled photonic devices and nanophotonic platforms for chiral sensing. In this paper, we introduce planar plasmonic metasurfaces, less than one-tenth of a wavelength thick, featuring nanocavities formed by three equilateral triangles. This configuration creates uniform, thin metasurfaces.

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