Publications by authors named "A Czeizel"
Orofacial clefts (OFCs), which include non-syndromic cleft lip with or without cleft palate (CL/P), are among the most common birth defects in humans, affecting approximately 1 in 700 newborns. CL/P is phenotypically heterogeneous and has a complex etiology caused by genetic and environmental factors. Previous genome-wide association studies (GWASs) have identified at least 15 risk loci for CL/P.
View Article and Find Full Text PDFCleft palate (CP) is a common birth defect occurring in 1 in 2,500 live births. Approximately half of infants with CP have a syndromic form, exhibiting other physical and cognitive disabilities. The other half have nonsyndromic CP, and to date, few genes associated with risk for nonsyndromic CP have been characterized.
View Article and Find Full Text PDFBirth Outcomes of Children Born to Women with Rheumatoid Arthritis.
Cent Eur J Public Health
June 2015
Aim: The aim of the study was to estimate the possible risk of adverse birth outcomes of children born to mothers with rheumatoid arthritis (RA).
Methods: The dataset of large population-based Hungarian Case-Control Surveillance System of Congenital Abnormalities from 1980-1996 was evaluated including 22,843 cases with congenital abnormalities and 38,151 matched controls without any defect.
Results: 36 cases (0.
Article Synopsis
- In 2013, approximately 2.8 million newborns died, highlighting the urgent need to focus on improving newborn health and reducing stillbirths as part of the Millennium Development Goals.
- A systematic prioritization exercise involving 200 researchers and 400 experts led to the identification of 205 research questions, which were evaluated by 91 specialists to determine the most critical areas for newborn health research from 2013 to 2025.
- The top research priorities emphasized enhancing known interventions like neonatal resuscitation, improving community health worker skills and diagnosis accuracy, as well as exploring advanced treatments for preterm babies, such as stable surfactant and new tocolytic agents.
In most patients affected by isolated infantile hypertrophic pyloric stenosis (IHPS) the etiology is largely unknown. Thus, the aim of this study was to estimate possible maternal risk factors in the origin of IHPS. The study samples included 241 cases with IHPS, 357 matched controls and 38,151 population controls without any defect in the population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996.
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