Publications by authors named "A Csosz"

Article Synopsis
  • - Dystonia is a rare movement disorder marked by muscle contractions leading to abnormal movements or postures, with common types being cervical dystonia (CD) and benign essential blepharospasm (BSP).
  • - The study involved 121 patients with an average age of 64, analyzing 30 genes related to CD and BSP, resulting in the identification of 209 different gene variants in 24 genes.
  • - The research confirmed nine genetic variations with clinical relevance and highlights the importance of genetic assessment in diagnosing focal dystonia, making it the first study of its kind in the Middle-European region.
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The ancient Hungarians originated from the Ural region in today's central Russia and migrated across the Eastern European steppe, according to historical sources. The Hungarians conquered the Carpathian Basin 895-907 AD, and admixed with the indigenous communities. Here we present mitochondrial DNA results from three datasets: one from the Avar period (7(th)-9(th) centuries) of the Carpathian Basin (n = 31); one from the Hungarian conquest-period (n = 76); and a completion of the published 10(th)-12(th) century Hungarian-Slavic contact zone dataset by four samples.

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MtDNA from the skeletal remains of two bodies buried in the grave No. F44 from Nitra-Šindolka (woman and child) was analysed. Cemeteries in Šindolka belong to the Bijelo Brdo culture, where Slavs and Magyars were buried in the 10th - 11th centuries.

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The genetic composition of the medieval populations of Central Europe has been poorly investigated to date. In particular, the region of modern-day Slovakia is a blank spot in archaeogenetic research. This paper reports the study of mitochondrial DNA (mtDNA) in ancient samples from the 9th-12th centuries originating from the cemeteries discovered in Nitra-Šindolka and Čakajovce, located in western Slovakia (Central Europe).

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A 9-bp deletion of the mtDNA is known as an anthropological marker of people with East-Asian origin. This 9-bp mtDNA deletion was analyzed in 1073 Hungarians with suspected mitochondrial disease and in 468 healthy control individuals. Fourteen cases with the 9-bp deletion were found in the cohort of mitochondrial patients, and one individual from 468 controls.

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