Publications by authors named "A Costanza"
Alpha Psychiatry
August 2024
Article Synopsis
- The study aims to compare sociodemographic factors, clinical features, comorbidities, and treatment patterns between patients with bipolar disorder type I (BD I) and type II (BD II).
- A total of 680 patients were assessed; findings revealed that BD I patients tend to be younger males who are single and unemployed, whereas BD II patients have a higher prevalence of suicide attempts and psychiatric comorbidities, along with more frequent alcohol use.
- The results highlight distinct profiles for BD I and II, emphasizing the need for tailored therapeutic strategies and improved clinical classifications to enhance treatment outcomes.
Expert Rev Neurother
October 2024
Article Synopsis
- Early diagnosis and treatment of bipolar disorder (BD) in youths lead to improved long-term outcomes, yet about one-third of affected patients do not receive adequate medication.
- The authors review current literature on managing BD in children and adolescents, primarily focusing on the effectiveness and side effects of various pharmacological treatments.
- Key findings indicate that while D2-blockers may have adverse effects, lurasidone is effective for acute juvenile bipolar depression, and lithium is beneficial for managing manic episodes; anticonvulsants are helpful as additional treatments for those not responding to first-line therapies, with no support for antidepressants in juvenile BD.
