Background: To provide insight into bone turnover, quantitative measurements of bone remodeling are required. Radionuclide studies are widely used in clinical care, but have been rarely used in the exploration of the bone in preclinical studies. We describe a bone planar scintigraphy method for frequent assessment of bone activity in mice across the growing period.
View Article and Find Full Text PDFWe use high-resolution [Formula: see text] data in multiple experiments to estimate the sources of error during coregistration of images acquired on separate preclinical instruments. In combination with experiments with phantoms, we completed imaging on mice, aimed at identifying the possible sources of registration errors, caused either by transport of the animal, movement of the animal itself, or methods of coregistration. The same imaging cell was used as a holder for phantoms and animals.
View Article and Find Full Text PDFDifferent environmental conditions under anesthesia may lead to unstable homeostatic conditions in rodents and therefore may alter kinetics. In this study, the impact of different heating conditions on PET imaging quantification was evaluated. Two groups of 6 adult female BALB/c nude mice with subcutaneously implanted tumors underwent microPET imaging after injection of F-labeled tetrafluoroborate or F-FDG.
View Article and Find Full Text PDFObjectives: Quantitative and qualitative image quality evaluation of two different dental CBCT scanners.
Methods: Two CBCT systems were evaluated in this study: one small field-of-view (FOV) (50-mm diameter) system that also allows two-dimensional (2D) dental panoramic imaging and one large FOV CBCT system (60-180-mm diameter). These devices were all tested with installed acquisition default modes and proprietary reconstruction software, enabling high-resolution bone imaging.
Objectives: Our aim was to conduct a quantitative and qualitative evaluation of high-resolution skull-bone imaging for dentistry and otolaryngology using different architectures of recent X-ray computed tomography systems.
Material And Methods: Three multi-slice computed tomography (MSCT) systems and one Cone-beam computed tomography (CBCT) system were used in this study. All apparatuses were tested with installed acquisition modes and proprietary reconstruction software enabling high-resolution bone imaging.