A prospective study on the usefulness of high-resolution intraoperative infrared thermography in intracranial tumors.

Introduction: Infrared thermography (IT) is a non-invasive real-time imaging technique with potential application in different areas of neurosurgery. Despite technological advances in the field, intraoperative IT (IIT) has been an underestimated tool with scarce reports on its usefulness during intracranial tumor resection. We aimed to evaluate the usefulness of high-resolution IIT with static and dynamic thermographic maps for transdural lesion localization, and diagnosis, to assess the extent of resection, and the occurrence of perioperative acute ischemia.

AlPaCas: allele-specific CRISPR gene editing through a protospacer-adjacent-motif (PAM) approach.

Gene therapy of dominantly inherited genetic diseases requires either the selective disruption of the mutant allele or the editing of the specific mutation. The CRISPR-Cas system holds great potential for the genetic correction of single nucleotide variants (SNVs), including dominant mutations. However, distinguishing between single-nucleotide variations in a pathogenic genomic context remains challenging.

A computing platform to analyze breast abnormalities using infrared images.

The present work shows a computational tool developed in the MATLAB platform. Its main functionality is to evaluate a thermal model of the breast. This computational infrastructure consists of modules in which manipulate the infrared images and calculate breast temperature profiles.

Dental arch definition in computed tomographs using two semi-automatic methods.

Computed tomography is a widely used image examination in dental imaging that provides an accurate location of oral structures and features, including the dental arch, which is an important anatomical feature. This study proposes two new semi-automatic methods for arch definition in CTs, with minimal user effort. This study includes 25 CT examinations.

Modeling the basic behaviors of Anesthesia Training in Relation to Puncture and Penetration Feedback.

Failure rates in spinal anesthesia are generally low in experienced hands. However, studies report a failure rate variation of 1% to 17% in this procedure. The aim of this study is to bring the main characteristics of in vivo procedure to the virtual reality simulated environment.