Assessment of complementary white matter microstructural changes and grey matter atrophy in the 6-OHDA-induced model of Parkinson's disease.

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Magnetic resonance imaging (MRI) offers a non-invasive means to study PD and its progression. This study utilized the unilateral 6-hydroxydopamine (6-OHDA) rat model of parkinsonism to assess whether white matter microstructural integrity measured using advanced free-water diffusion tensor imaging metrics (fw-DTI) and gray matter density using voxel-based morphometry (VBM) can serve as imaging biomarkers of pathological changes following nigrostriatal denervation.

Predictors of outcome in patients with presumed reversible cerebral vasoconstriction syndrome (RCVS).

Introduction: Reversible cerebral vasoconstriction syndrome (RCVS) is thought to be benign by nature, but a proportion of patients still suffer from neurological deficits on follow-up.

Objective: To understand what factors may influence a patient's recovery from RCVS.

Methods: The Clinical Research Data Warehouse at this institution was employed to search the medical records for patients with diagnosis and treatment of RCVS (2010-2021).

Trace organic compounds and photosensitizing activity in Salvadoran surface and tap water sources: A first look.

Despite their potential risks to human health and the environment at ng/L to μg/L concentrations, there has been relatively little effort to measure trace organic compounds (TOrCs) in surface waters of Central America. The concentrations of eighteen TOrCs detected at eleven surface water sites in the Lempa River basin of El Salvador and four sources of drinking water for the cities of San Salvador, Antiguo Cuscatlán, Soyapango, and Santa Tecla are reported here. All samples were analyzed via liquid chromatography with tandem mass spectrometry (LC-MS/MS).

Variations in Some Features of Oral Health by Personality Traits, Gender, and Age: Key Factors for Health Promotion.

: Oral diseases remain among the most common non-communicable diseases worldwide, affecting almost half of the world's population. This is partly because there has been a separation of the mouth from the rest of the body and human health, and psychological aspects such as personality, thoughts, and emotions are not taken into account in the dental office. The objective was to analyze the relationship between oral health conditions and personality traits in adult patients who underwent dental treatment at the Center for Health Studies and Services.