Publications by authors named "A Colom"

Translation of photophysical properties of fluorescent sensors from solution to solid-gas environments functionalized surfaces constitutes a challenge in chemistry. In this work, we report on the chemical synthesis, barium capture ability and photophysical properties of two families of monocolor and bicolor fluorescent sensors. These sensors were prepared to capture barium cations that can be produced in neutrinoless double beta decay of Xe-136.

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The ESCRT-III-like protein Vipp1 couples filament polymerization with membrane remodeling. It assembles planar sheets as well as 3D rings and helical polymers, all implicated in mitigating plastid-associated membrane stress. The architecture of Vipp1 planar sheets and helical polymers remains unknown, as do the geometric changes required to transition between polymeric forms.

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Measuring forces within living cells remains a technical challenge. In this Tutorial, we cover the development of hydrophobic mechanosensing fluorescent probes called Flippers, whose fluorescence lifetime depends on lipid packing. Flipper probes can therefore be used as reporters for membrane tension via the measurement of changes in their fluorescence lifetime.

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Article Synopsis
  • The text discusses a specific bacterium found in tropical and subtropical regions that can cause severe illnesses in humans and animals; the focus is on synthesizing new acyl homoserine lactones (HSLs) to evaluate their ability to inhibit bacterial communication (quorum sensing).
  • The synthesized HSLs were tested for their effectiveness in reducing the production of specific signaling molecules and biofilms, with the most effective compound being -(2-hexadecynoyl)-l-homoserine lactone, which showed significant activity at various concentrations without being toxic to Vero cells.
  • Molecular docking studies further indicate that this compound interacts favorably with the CviR receptor, suggesting that these novel H
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