Publications by authors named "A Colantuoni"

Acute and chronic hypertension causes cerebral vasculopathy, increasing the risk of ischemia and stroke. Our study aimed to compare the effects of arterial pressure reduction on the pial microvascular responses induced by hypoperfusion and reperfusion in spontaneously hypertensive Wistar rats, desamethasone-induced hypertensive Wistar rats and age-matched normotensive Wistar rats fed for 3 months with a normal diet or normal diet supplemented with L-arginine or Taurisolo or L-arginine plus Taurisolo. At the end of treatments, the rats were submitted to bilateral occlusion of common carotid arteries for 30 min and reperfusion.

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Article Synopsis
  • Obesity is linked to various diseases, and diet and exercise are key treatments for reducing it.
  • A study evaluated the impact of a hypocaloric diet combined with cinchona supplementation on weight loss and body composition in obese adults over two months.
  • Results showed that the group receiving the cinchona supplement experienced greater improvements in body composition and metabolic parameters compared to the placebo group.
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Caloric restriction (CR) and dietary nitrate supplementation are nutritional interventions with pleiotropic physiological functions. This pilot study investigates the combined effects of CR and nitrate-rich beetroot juice (BRJ) on metabolic, vascular, and cognitive functions in overweight and obese middle-aged and older adults. This was a two-arm, parallel randomized clinical trial including 29 participants allocated to CR + BRJ ( = 15) or CR alone ( = 14) for 14 days.

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